Explainer: What is the Covid BA.5 variant and why is it reinfecting so many people?

Published July 13, 2022
People wait to take coronavirus disease tests at a pop-up testing site in New York City, US, July 11. — Reuters
People wait to take coronavirus disease tests at a pop-up testing site in New York City, US, July 11. — Reuters

BA.5, part of the Omicron family, is the latest coronavirus variant to cause widespread waves of infection globally.

According to the World Health Organisation’s (WHO) most recent report, it was behind 52 per cent of cases sequenced in late June, up from 37pc in one week. In the United States, it is estimated to be causing around 65pc of infections.

Rising case numbers

BA.5 is not new. First identified in January, it has been tracked by the WHO since April.

It is a sister variant of the Omicron strain that has been dominant worldwide since the end of 2021 and has already caused spikes in case rates — even with reduced testing — in countries, including South Africa, where it was first found, as well as the United Kingdom, parts of Europe, and Australia.

Coronavirus cases worldwide have now been rising for four weeks in a row, WHO data showed.

Why is it spreading

Like its closely related sibling, BA.4, BA.5 is particularly good at evading the immune protection afforded either by vaccination or prior infection.

For this reason, “BA.5 has a growth advantage over the other sublineages of Omicron that are circulating,” Maria Van Kerkhove, the WHO’s technical lead on Covid-19, told a news briefing on Tuesday.

For many people, this means that they are getting re-infected, often even a short time after having Covid-19. Van Kerkhove said the WHO is assessing reports of re-infections.

“We have ample evidence that people who’ve been infected with Omicron are getting infected with BA.5. No question about it,” said Gregory Poland, a virologist and vaccine researcher with the Mayo Clinic in Rochester, Minnesota.

If that seems particularly common now, it could be simply because so many people got Omicron, researchers have suggested.

No more severe

While rising cases have caused more hospitalisations in some countries, deaths have not gone up dramatically.

This is largely because vaccines continue to protect against severe illness and death, if not infection, and manufacturers and regulators are also looking at tweaked vaccines that directly target the newer Omicron variants.

There is also no evidence that BA.5 is more dangerous than any of the other Omicron variants, the WHO’s Van Kerkhove stressed, although spikes in cases can put health services under pressure and risk more people getting long Covid.

The WHO and other experts have also said that the ongoing pandemic — prolonged by vaccine inequity and the desire in many countries to “move beyond” Covid-19 — would only lead to more new and unpredictable variants.

Scientists are already drawing attention to BA.2.75, first identified in India, which has a large number of mutations and is spreading fast.

The WHO said on Tuesday that the pandemic remained a global health emergency, and countries should consider public health measures like masking and social distancing when cases surge, alongside vaccinations.

“What people fundamentally don’t understand is that when there is this high level of community transmission, this will mutate,” Poland said. “Who knows what’s going to come next. We are playing with fire.”

Opinion

Editorial

Furtive measures
Updated 07 Sep, 2024

Furtive measures

The entire electoral exercise has become riddled with controversy, yet ECP seems unwilling to address the lingering questions about the polls.
PCB hot seat
Updated 07 Sep, 2024

PCB hot seat

MOHSIN Naqvi is facing criticism from all quarters. Pakistan’s cricket board chief, who is also the country’s...
Rapes most foul
07 Sep, 2024

Rapes most foul

UNTIL the full force of the law is applied on perpetrators, insecurity will stalk Pakistan’s girl children and...
Positive overtures
Updated 06 Sep, 2024

Positive overtures

It is hoped politicians refusing to frame Balochistan’s problems in black and white is taken as a positive overture by the province's people.
Capital poll delay
06 Sep, 2024

Capital poll delay

THE ECP has cancelled the local government elections in Islamabad for the third time subsequent to a recent ...
Perks galore
06 Sep, 2024

Perks galore

A parasitic bureaucracy still upholds colonial customs whereby a struggling citizenry and flood victims are subservient to status.