The funeral prayers for Sabika Sheikh, a 17-year-old Pakistani exchange student who was killed in a Texas school shooting last week, were offered at Karach's Hakeem Saeed Ground at 9am on Wednesday.
Sheikh was among the 10 people gunned down at a high school in Santa Fe last Friday when a heavily armed student opened fire on classmates.
Security arrangements were tight at the venue, where a number of government officials and political leaders, including Sindh Chief Minister Murad Shah, Sindh Governer Muhammad Zubair, Sindh Home Minister Sohail Anwar Siyal, Pak Sarzameen Party chief Mustafa Kamal, Pakistan Tehreek-i-Insaf's (PTI) Halim Adil Sheikh and others attended her funeral prayers.
About 100 police officers were deployed at the ground, where a bomb disposal squad had conducted a sweep to ensure security for attendees.
She was laid to rest at the Azimpura graveyard in Shah Faisal Colony.
"My daughter is a martyr and martyrs don't die," Sheikh's father said after the prayers.
Officials participating the ceremony labelled her killing an act of terrorism.
"The whole nation stands by the Pakistani girl who was martyred in a terrorist attack in the US. May God give patience to her parents and family," governor Mohammad Zubair told reporters after the funeral.
Sabika, a Karachi teenager whose family lives in the Gulshan-i-Iqbal area, was studying at Santa Fe High School in Texas on a US State Department scholarship under the Kennedy-Lugar Youth Exchange and Study (YES) programme.