A spike in Israeli-Palestinian violence on Thursday left three Arabs killed and a dozen Israeli troops wounded in a rash of attacks and clashes a week after the Trump administration released its long-anticipated Mideast plan.

The new spate of attacks places the plan — which was already considered a long-shot because it greatly favours Israel and was rejected outright by the Palestinians — on even shakier ground, and sparked fears of a return to deadly rounds of violence of the past. The plan has triggered calls by Israeli nationalists for Israel to annex parts of the West Bank — land Palestinians want for their hoped-for state — and has set off tensions in the region.

But they erupted more fiercely on Thursday, in the deadliest day of violence in months.

The Trump plan “created this environment of tension and escalation”, Nabil Abu Rdeneh, a spokesman for Palestinian President Mahmoud Abbas, told the official Palestinian news agency, WAFA.

Early in the day, a Palestinian motorist slammed his car into a group of Israeli soldiers, wounding 12 before fleeing the scene, the Israeli military said. In the West Bank, two Palestinians died after clashes broke out with Israeli troops, according to Palestinian hospital officials.

And later, Israeli police said they shot and killed an Arab citizen of Israel who opened fire at forces in Jerusalem’s Old City, lightly wounding an officer.

Israeli military spokesman Lt Col Jonathan Conricus said one of the 12 injured soldiers in Jerusalem was seriously hurt, the others were lightly injured. Israeli police spokesman Micky Rosenfeld said the incident was being treated as a “terror attack”, and said Israeli forces were searching for the assailant.

Palestinian hospital officials said a 19-year-old was killed in clashes in the West Bank city of Jenin. Six others were wounded in the confrontation. In a separate incident also in Jenin, a member of the Palestinian security forces who was shot by Israeli troops later died. That violence came just hours after Israeli forces shot and killed a 17-year-old Palestinian during clashes with demonstrators elsewhere in the West Bank on Wednesday.

“Attacks from Gaza, an attack in Jerusalem, signs of a rise in hostile activity in Jenin. Yesterday friction in Hebron. We are not trying to escalate the situation while understanding the complexity and sensitivity of the situation,” Conricus said, stopping short of directly linking the spate of violence to Trump’s plan.

In the first Jerusalem incident, the troops were out on a late-night “educational heritage tour”, walking near a popular entertainment district in Jerusalem when the motorist rammed his car into them and fled.

While it did not claim responsibility for the attack, the Islamic Jihad militant group praised the car ramming as “the beginning of a new confrontation over Trump’s plan”.

Israeli Prime Minister Benjamin Netanyahu vowed to have the assailant apprehended. “It’s just a matter of time — and not much time,” he said in a statement.

Such acts of violence were common in Jerusalem during a low-level wave of near-daily attacks over the last decade, but they tapered off and car rammings have become infrequent in recent years.

Conricus said troops were carrying out the demolition of a home in the West Bank belonging to a militant allegedly involved in a deadly attack. He said there was a “sizable riot” at the scene by Palestinians who threw Molotov cocktails at troops, who then came under sniper fire. Conricus said forces responded to the violence with their own sniper fire, saying a Palestinian shooter was killed.

Jenin governor Akram Rajoub said the 19-year-old casualty was a student at an academy that trains budding police officers, and was throwing stones at the troops.

Also Thursday, Israel struck Hamas positions in the Gaza Strip after three mortar shells were fired at Israel. There was no immediate report of injuries on either side.

Unveiled last week at the White House with much fanfare, Trump’s plan envisions a disjointed Palestinian state that turns over key parts of the West Bank to Israel. It sides with Israel on key contentious issues that have bedevilled past peace efforts, including borders and the status of Jerusalem and Jewish West Bank settlements, and attaches nearly impossible conditions for granting the Palestinians their hoped-for state.

The plan was greeted ecstatically in Israel, with Netanyahu vowing to speed ahead with annexing parts of the West Bank. But under pressure from the US administration, he appears to be scaling back on that promise.

The Palestinians dismissed the plan as “nonsense” and have promised to resist it.

The Palestinians, as well as much of the international community, view the settlements in the West Bank and annexed east Jerusalem — territories seized by Israel in the 1967 war — as illegal and a major obstacle to peace.