MIRAMSHAH: A US drone strike late Tuesday killed at least four militants in northwest Pakistan's lawless tribal belt on the border with Afghanistan, local security officials said.

The drone fired two missiles at a guesthouse in Mir Ali, about 25 kilometres (16 miles) east of Miramshah, the main town in North Waziristan tribal district, the officials said.

“The guesthouse was completely destroyed. At least four militants have been killed in this US drone attack,” said a security official in Mir Ali. “Five other militants were injured.” Taliban and Al-Qaeda-linked militants have carved out strongholds in the tribal belt where they plot attacks on Pakistani, Afghan and Western targets.

Another security official in Miramshah confirmed the strike and put the death toll at six.

Both officials said they had reports that there were some foreign militants among the dead.