WASHINGTON: Secretary of State Hillary Clinton came out guns blazing on Wednesday, angrily dismissing Republican charges of a cover-up over the deadly Benghazi attack and warning of a rise in militant extremism.

At times emotional and often fiery, Clinton gave no ground to congressional critics still seeking to determine why the administration at first blamed the September 11 attack on a protest outside the US mission in eastern Libya.

“With all due respect, the fact is, we had four dead Americans. Was it because of a protest or because of guys out for a walk one night and (who) decided to go kill some Americans?” she told the tense hearing.

“What difference does it make?” she demanded, thumping her fist on the table as Senator Ron Johnson repeatedly asked her why the administration had falsely initially linked the attack to protests against an anti-Islam Internet video.

“It is our job to figure out what happened and do everything we can to prevent it from ever happening again, senator,” she said.

She insisted there was no administration cover-up of the events of the night, when dozens of heavily-armed al Qaeda-linked militants overran the compound and a nearby CIA-run annex, setting off an eight-hour firefight in which four people, including US ambassador Chris Stevens, were killed.

“Nothing could be further from the truth,” Clinton insisted, stressing that in the days afterwards the administration did not have “a clear picture yet.”

In one of her last major appearances before stepping down at the end of the month, Clinton showed no signs of the ill-health which plagued her in December.

She also choked back a sob as she described having to call the families with the news that Stevens, and information manager Sean Smith, had been killed.

“This is not just a matter of policy. It's personal. I stood next to President Obama as the Marines carried those flag-draped caskets off the plane at Andrews” air force base, Clinton told the senators.

“I put my arms around the mothers and fathers, the sisters and brothers, the sons and daughters, and the wives left alone to raise their children.”

And she urged senators to learn from the attack as they confront a rapidly evolving political landscape in the wake of the Arab Spring.

“Benghazi didn't happen in a vacuum,” Clinton said.

“The Arab revolutions have scrambled power dynamics and shattered security forces across the region,” she told the Senate Foreign Relations committee.

But top Republican senators rejected her explanations, with Senator Rand Paul suggesting she should have been fired for not reading requests for additional security.

“Had I been president at the time and I found that you did not read the cables from Benghazi, you did not read the cables from Ambassador Stevens, I would have relieved you of your post. I think it's inexcusable,” he said.

Senator John McCain also “categorically” rejected some answers, saying four months on the American public still did not have “basic information.”

”It's a tragedy when we lose four brave Americans, there are many questions that are unanswered. And the answers, frankly, that you've given this morning are not satisfactory to me,” he told Clinton.

He said he still wanted to know why US ambassador to the United Nations Susan Rice said days after the attack that it was triggered by a spontaneous protest outside the mission, when no such demonstration had taken place.

Appearing at her last congressional hearings as secretary of state, Clinton reiterated that she took full responsibility for deficiencies at the mission and insisted she had taken steps to boost security in high-threat regions.

The FBI was also “following some very promising leads” as they investigate exactly who was behind the Benghazi attack, she said, warning that “no one should doubt” President Barack Obama's promise that America would respond.

But Clinton stressed that Congress ultimately had the power to better fund security, highlighting how the State Department's 2012 budget for diplomatic security was $340 million, or 10 per cent, less than requested.

She had been initially set to testify in December after a scathing internal inquiry blamed “grossly inadequate” security at the outpost in Benghazi.

But Clinton was forced to send two deputy secretaries instead when she fell ill with a stomach bug, later suffering a concussion which led to a blood clot.

Her testimony now comes on the eve of Thursday's Senate hearing to confirm her successor, John Kerry, who is expected to be easily voted in and could take over within days as the top US diplomat.